Product Datasheet
TERF1 Antibody
Catalog Number: 35974
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P54274
NCBI Gene ID: 7013
Gene Accssion: BC029378
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human telomeric repeat binding factor (NIMA-interacting) 1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TERF1 protein.
- Background:
- This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
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