Product Datasheet
MAP4K5 Antibody
Catalog Number: 35950
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y4K4
NCBI Gene ID: 11183
Gene Accssion: BC036013
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human mitogen-activated protein kinase kinase kinase kinase?
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- KHS; GCKR; KHS1; MAPKKKK5
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAP4K5 protein.
- Background:
- This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.?
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