Product Datasheet
TAT Antibody
Catalog Number: 35946
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17735
NCBI Gene ID: 6898
Gene Accssion: BC130534
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human tyrosine aminotransferase
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- ATTY; cytosolic;Tyrosine aminotransferase
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TAT protein.
- Background:
- This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.
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