Product Datasheet
SEMA3G Antibody
Catalog Number: 35912
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NS98
NCBI Gene ID: 56920
Gene Accssion: BC098137
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
- appl_detail:
- Western blotting: 1:200-1:1000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SEMA3G protein.
- Background:
- Semaphorins?are a class of secreted and membrane?proteins?that act as?axonal?growth cone?guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric?receptor?complexes. They are usually cues to deflect axons from inappropriate regions, especially important in?neural system?development. The major class of proteins that act as their receptors are called?plexins.SEMA3G possesses anti-migration and anti-invasion ability. SEMA3G inhibited tumor cell migration and invasion, which may be obtained through cell autonomous or paracrine mechanisms, and SEMA3G is a potential target for antitumor migration and invasion.
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