Product Datasheet
S100A1 Antibody
Catalog Number: 35908
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P23297
NCBI Gene ID: 6271
Gene Accssion: BC014392
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human S100 calcium binding protein A1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- S100; S100A; S100-alpha
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total S100A1 protein.
- Background:
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
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