Product Datasheet  
PRMT7 Antibody  
Catalog Number: 35889  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9NVM4
    NCBI Gene ID: 54496
    Gene Accssion: BC000146
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human Protein arginine methyltransferase 7
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:2000
  • other_names：  
  • ANM7;FLJ10640;KIAA1933
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PRMT7 protein.
  • Applications：  
  • WB
  • Background：  
  • Protein arginine methyltransferase 7?is a?protein?that in humans is encoded by the?PRMT7?gene.?Arginine?methylation?is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using?S-adenosylmethionine?(AdoMet) as the methyl donor. Arginine methylation is implicated in?signal transduction, RNA transport, and?RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).



 
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