Product Datasheet
RCHY1 Antibody
Catalog Number: 35879
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96PM5
NCBI Gene ID: 25898
Gene Accssion: BC047393
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- ARNIP; CHIMP; PIRH2; PIRH2E; PIRH2F; RNF199; ZNF363; hARNIP; PRO1996
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RCHY1 protein.
- Background:
- The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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