Product Datasheet
OASL Antibody
Catalog Number: 35849
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15646
NCBI Gene ID: 8638
Gene Accssion: BC117408
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human 2'-5'-oligoadenylate synthetase-like
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total OASL protein.
- Background:
- OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes, the 2-5A synthetases or OASs
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