Product Datasheet  
OASL Antibody  
Catalog Number: 35849  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q15646
    NCBI Gene ID: 8638
    Gene Accssion: BC117408
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human 2'-5'-oligoadenylate synthetase-like
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100
  • other_names:  
  • OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total OASL protein.
  • Applications:  
  • WB IHC
  • Background:  
  • OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes, the 2-5A synthetases or OASs



 
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