Product Datasheet
NCK1 Antibody
Catalog Number: 35832
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P16333
NCBI Gene ID: 4690
Gene Accssion: BC006403
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human NCK adaptor protein 1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- NCK; nck-1; NCKalpha
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NCK1 protein.
- Background:
- The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
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