Product Datasheet  
CHRNA4 Antibody  
Catalog Number: 35829  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P43681
    NCBI Gene ID: 1137
    Gene Accssion: BC096290/P43681
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 4 (neuronal)
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total CHRNA4 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.?



 
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