Product Datasheet
MPO Antibody
Catalog Number: 35820
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P05164
NCBI Gene ID: 4353
Gene Accssion: BC130476
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human myeloperoxidase
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- MPO;Myeloperoxidase;PERM
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MPO protein.
- Background:
- Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.?
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