Product Datasheet
MMP16 Antibody
Catalog Number: 35818
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51512
NCBI Gene ID: 4325
Gene Accssion: BC069500
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human matrix metallopeptidase 16 (membrane-inserted)
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MMP16 protein.
- Background:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
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