Product Datasheet
ST14 Antibody
Catalog Number: 35811
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y5Y6
NCBI Gene ID: 6768
Gene Accssion: BC030532
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human suppression of tumorigenicity 14 (colon carcinoma)
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- HAI; MTSP1; SNC19; MT-SP1; PRSS14; TADG15; TMPRSS14
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ST14 protein.
- Background:
- The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors.
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