Product Datasheet
LAIR1 Antibody
Catalog Number: 35800
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6GTX8
NCBI Gene ID: 3903
Gene Accssion: BC027899
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human leukocyte-associated immunoglobulin-like receptor 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:15-1:50
- other_names:
- CD305; LAIR-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LAIR1 protein.
- Background:
- The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.?
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