Product Datasheet
IRF6 Antibody
Catalog Number: 35786
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14896
NCBI Gene ID: 3664
Gene Accssion: BC014852
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human interferon regulatory factor 6
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IRF6 protein.
- Background:
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
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