Product Datasheet
ITGB6 Antibody
Catalog Number: 35783
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P18564
NCBI Gene ID: 3694
Gene Accssion: BC121178
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human integrin, beta 6
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- ITGB6;ITB6;beta 6; integrin
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ITGB6 protein.
- Background:
- Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. Integrin, beta 6 has been shown to interact with FHL2. Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
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