Product Datasheet
HSPH1 Antibody
Catalog Number: 35773
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q92598
NCBI Gene ID: 10808
Gene Accssion: BC037553
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human Heat shock 105kDa/110kDa protein 1
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- HSP105; HSP105A; HSP105B; NY-CO-25
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HSPH1 protein.
- Background:
- Heat shock protein 105 kDa?is a?protein?that in humans is encoded by the?HSPH1?gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
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