Product Datasheet
ARHGEF5 Antibody
Catalog Number: 34996
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q12774
NCBI Gene ID: 7984
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ARHGEF5.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- ARH5; guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor 5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ARHGEF5 protein.
- Background:
- Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Chan A.M.-L., Oncogene 9:1057-1063(1994).
Jikuya H., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 424:157-164(2003)
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