Product Datasheet
CPA5 Antibody
Catalog Number: 34547
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8WXQ8
NCBI Gene ID: 93979
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CPA5.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Carboxypeptidase A5;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CPA5 protein.
- Background:
- Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008]
Maestrini E., Mol. Psychiatry 7:289-301(2002).
Moore G.E., J. Med. Genet. 40:249-256(2003).
Sugano S., Nat. Genet. 36:40-45(2004)
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