Product Datasheet
CES2 Antibody
Catalog Number: 34546
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O00748
NCBI Gene ID: 8824
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human CES2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Carboxylesterase 2; carboxylesterase 2 (intestine; liver); CE-2; CES2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CES2protein.
- Background:
- Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.
Schwer H., Biochem. Biophys. Res. Commun. 233:117-120(1997).
Pindel E.V., J. Biol. Chem. 272:14769-14775(1997).
Sone T., Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
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