Product Datasheet
CHST8 Antibody
Catalog Number: 34536
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9H2A9
NCBI Gene ID: 64377
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CHST8.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate sulfotransferase 8; EC 2.8.2.-; GalNAc-4-O-sulfotransferase 1; GalNAc-4-ST1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CHST8 protein.
- Background:
- Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin.
Okuda T., J. Biol. Chem. 275:40605-40613(2000).
Hiraoka N., Glycobiology 11:495-504(2001).
Barret A., J. Biol. Chem. 280:10516-10523(2005).
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