Product Datasheet
CLIP1 Antibody
Catalog Number: 34529
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P30622
NCBI Gene ID: 6249
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CLIP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CLIP-170; CLIP1; Cytoplasmic linker protein-170 alpha-2; Reed- Sternberg intermediate filament associated protein; REST
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CLIP1 protein.
- Background:
- Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.
Bilbe G., EMBO J. 11:2103-2113(1992).
Pierre P., Cell 70:887-900(1992). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
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