Product Datasheet
CNN2 Antibody
Catalog Number: 34522
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q99439
NCBI Gene ID: 1265
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CNN2.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- Calponin H2; smooth muscle; CLP2; CNN2; Neutral calponin
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CNN2 protein.
- Background:
- Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Masuda H., J. Biochem. 120:415-424(1996).
Kuromitsu J., Mol. Cell. Biol. 17:707-712(1997).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).
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