Product Datasheet  
BCL2L12 Antibody  
Catalog Number: 34482  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9HB09
    NCBI Gene ID: 83596
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human BCL2L12.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total BCL2L12 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

    Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
    Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
    Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].



 
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