Product Datasheet
ATP5H Antibody
Catalog Number: 34446
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O75947
NCBI Gene ID: 10476
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of humanATP5H.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- ATP synthase D chain; mitochondrial; ATP synthase; H+ transporting; mitochondrial F0 complex
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ATP5H protein.
- Background:
- Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha3beta3 subcomplex and subunit a/ATP6 static relative to the rotary elements.
Lee H.C., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Mao Y.M., Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
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