Product Datasheet  
SCNN1D Antibody  
Catalog Number: 34408  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P51172
    NCBI Gene ID: 6339
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human SCNN1D.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:3000

  • other_names：  
  • Amiloride-sensitive sodium channel subunit delta; Epithelial Na(+) channel subunit delta; Delta-ENaC; SCNED; Nonvoltage-gated sodium channel 1 subunit delta
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SCNN1D protein.
  • Applications：  
  • WB
  • Background：  

  • Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

    Waldmann R., J. Biol. Chem. 270:27411-27414(1995).
    Ota T., Nat. Genet. 36:40-45(2004).
    Gregory S.G., Nature 441:315-321(2006).




 
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