Product Datasheet  
AKR1C2 Antibody  
Catalog Number: 34400  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P52895
    NCBI Gene ID: 1646
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human AKR1C2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • 3-alpha-HSD3; AK1C2; AKR1C-pseudo; aldo-keto reductase family 1 member C2; BABP
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total AKR1C2 protein.
  • Applications：  
  • WB
  • Background：  
  • Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

    Qin K.-N., J. Steroid Biochem. Mol. Biol. 46:673-679(1993).
    Ciaccio P.J., Biochim. Biophys. Acta 1186:129-132(1994).
    Qin K.-N., Gene 149:357-361(1994).




 
© Signalway Biotechnology All Rights Reserved.