Product Datasheet
PAFAH1B3 antibody
Catalog Number: 31990
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UJW9
NCBI Protein#: BC003016
- Form of Antibody:
- pH7.4 PBS, 0.05% NaN3, 40% Glycerol
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein of human PAFAH1B3
- appl_detail:
- WB dilution:1:1000-1:5000
IHC dilution:1:50-1:200
- Purification:
- Antigen affinity purification
- Background:
- This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
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