Product Datasheet
ST8SIA1 Polyclonal Antibody
Catalog Number: 31727
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q92185
NCBI Gene ID:6489
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ST8SIA1 (NP_003025.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- ST8SIA1; GD3S; SIAT8; SIAT8-A; SIAT8A; ST8SiaI; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- Purification:
- Affinity purification
- Background:
- Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
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