Product Datasheet
SLC1A1 Antibody
Catalog Number: 31187
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O95452
Gene ID:10804
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 181-195 amino acids of Human Solute carrier family 1 member 1
- other_names:
- Solute carrier family 1 member 1, EAAT3, EAAC1
- Specificity:
- The antibody detects endogenous level of total SLC1A1 protein.
- Background:
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
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