Product Datasheet
ANGPTL3 Antibody
Catalog Number: 31029
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q04695
Gene ID:3872
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3
- other_names:
- Angiopoietin-related protein 3, FHBL2, ANGPT5
- Specificity:
- The antibody detects endogenous level of total ANGPTL3 protein.
- Applications:
- ELISA WB IHC
- Background:
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
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