Product Datasheet  
AFP Antibody  
Catalog Number: 31001  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P63261
    Gene ID:71
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 260-609 amino acids of human alpha-fetoprotein
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 69kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • alpha-fetoprotein, FETA, HPAFP
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total AFP protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.




 
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